Bill Gross talks about analyzing his 100 startups and others from the marketplace around him.
In conclusion he says:
Timing for us is product market-fit and demand.
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Rank | Start-Up | Score | Team | Backing | Opportunity |
1 | DarwinAI | 96 | 5 | 7 | 4 |
2 | SkyWatch | 93 | 4 | 8 | 4 |
3 | Zoom.ai | 90 | 4 | 7 | 4 |
4 | Green Tank Technologies | 90 | 5 | 5 | 4 |
5 | Acerta | 88 | 5 | 7 | 3 |
6 | Avro | 87 | 4 | 8 | 3 |
7 | Jiffy | 87 | 5 | 6 | 3 |
8 | Cinchy | 86 | 5 | 6 | 3 |
9 | Hostaway | 83 | 5 | 6 | 3 |
10 | NorthOne | 82 | 5 | 6 | 3 |
DarwinAI, Skywatch, Acerta, and Avro are from K-W, while the rest are from Toronto.
DarwinAI is the next evolution in A.I. development. Based on distinguished scholarship by an award-winning team led by a Canada Research Chair in A.I., DarwinAI takes the guesswork out of building better A.I.
Through our patented Generative Synthesis Making A.I. work for anyone, anywhere, anytime. |
SkyWatch provides a digital infrastructure for the distribution of Earth observation data and derived intelligence providing application developers with a single access point to the world’s best Earth observation data and advanced processing algorithms.
SkyWatch EarthCache is a cloud-based platform with comprehensive APIs to facilitate machine-to-machine integration, informative dashboards to monitor usage, and an easy-to-use code builder to rapidly develop associated applications. Adopting EarthCache into your development environment eliminates the need for multiple integration points, legal contracts, pricing and payment models, and costly multi-point searches. Instead, EarthCache allows the development teams to focus on the business application and in delivering actionable intelligence to the end-user. |
Productivity is wasted as employees juggle time-consuming admin tasks between priority work. Zoom.ai is a chat-based productivity tool that helps employees to offload and automate everyday tasks including searching for files, scheduling meetings, generating documents and much more. Get back to your higher value work by using Zoom.ai — all within your favourite chat platform. |
A global leader in vaporizing hardware and product design, they are committed to shaping the industry by developing innovative technologies. At Green Tank Technologies, they know that producers and extractors spend years and tons of money developing their quality bud and oil. They set out on a mission to provide quality devices that deliver full flavor and the ultimate user experience. Green Tank designs, develops, and produces industry leading quality vaporization hardware with True-Taste Ceramic Core Technology for full flavor and maximum terpene profiles. |
Acerta provides a platform that uses machine learning and AI to detect malfunctions and predict failures in real-time for vehicles and their systems (eg. engines, transmission, pumps, motors, etc.). Acerta is a unique platform in that it is able to leverage the data from across the vehicle lifecycle, starting from development and testing, to manufacturing and on-road driving. We are thus ensuring quality throughout the vehicle life.
We have started making an impact for manufacturers today by applying our platform and analysis during assembly. In our most recent deployment we were able to reduce warranties by 30% by identifying complex patterns in testing data that were indicative of defects. We also saved the engineers from having to inspect 4,000 plots per failure – our models automatically identified just 10 that engineers used for troubleshooting. Our recent projects with autonomous vehicle manufacturers are also already bearing fruits! We are introducing important safety features for braking and steering, as well as passenger comfort features. |
Avro Life Science is developing skin patches for generic drug delivery, focusing on therapeutics for children and the elderly. The core of our technology is a novel biopolymer which is used as a platform for passive transdermal drug delivery of small molecules and drugs. |
Jiffy is an online platform that connects homeowners with home service providers in real time, based on proximity and availability. These professionals are all pre-vetted. |
Cinchy is the leading provider of enterprise data collaboration technology, the revolutionary alternative to data sharing. |
Hostaway is an easy-to-use channel manager for vacation rental hosts that want to increase their client base. It uses existing listings and creates new ones for all the sales channels the host wants to use. |
Our purpose is to make you and your business more successful by bringing business banking into the 21st century.
We’re building Canada’s first mobile-first API-based banking platform that helps startups and small businesses bank, manage their finances, and integrate all of their financial tools in a simple and intuitive way. Join us and our growing community at www.northone.io |
We are not economists. We do follow a few market indicators that help us decide relative states of health of the investment market and relative states of health of the economy.
One indicator that tells us that there may be less long-term money in the investment markets is the 2-10 US Treasury spread. This is signaling lean times ahead. You can find more about this online. When there is a spread inversion there is a strong market to a near-term recession.
The indicators we follow show that there are either fewer ideas in the marketplace now or less money. Here’s the information that is forming our opinion:
Canadian companies publishing getting seed rounds.
Year | Period | Number of Published Seed Rounds |
2016 | Jan-Nov | 223 |
2017 | Jan-Nov | 198 |
2018 | Jan-Nov | 162 |
You can see for the same period in the past three years there is a steady decline in companies publishing their seed rounds. This may be that we’ve decided this is not important, or it may also suggest fewer ideas, or it may suggest less money available.
Canadian companies being acquired:
Year | Period | Number of Canadian Acquisitions |
2016 | Jan-Nov | 370 |
2017 | Jan-Nov | 403 |
2018 | Jan-Nov | 361 |
There is a drop from last year in this time period and we are also less than 2016, which isn’t a clear trend but it does show a drop in the activity of the marketplace.
Finally,
Global IPOs:
Year | Period | Number of Global IPOs |
2016 | Jan-Nov | 45 |
2017 | Jan-Nov | 238 |
2018 | Jan-Nov | 247 |
This seems great. Companies are going public at an astounding rate.
But if we look at the IPO activity before the last recession we see
Year | Period | Number of Global IPOs |
2005 | Jan-Nov | 20 |
2006 | Jan-Nov | 20 |
2007 | Jan-Nov | 37 |
Almost as if the financiers taking companies public really wanted to get to the markets before the recession.
If we look at recession years that followed we see:
Year | Period | Number of Global IPOs |
2008 | Jan-Nov | 8 |
2009 | Jan-Nov | 17 |
So basically there isn’t enough money in the market to finance all the companies, or perhaps a company is hit by the recession and it’s decided to wait for a better balance sheet.
Regardless, recessions are bad for the investment environment and we feel one is coming. The goal at TheMIN is to discuss what we can do to stay winners.
]]>The averages look like this:
Ave Yrs to IPO | Avg Valuation at IPO | Time-Value Correlation |
8.2 | $494,223,935.16 | -39% |
One conclusion is that the longer a company takes to reach an IPO the lower its valuation at IPO time. If we split the cohort into two pieces and group the fastest to IPO with the slowest to IPO we see a few other interesting things.
Ave Yrs to IPO (Fastest) | Avg Valuation at IPO | Time-Value Correlation |
3.8 | $603,441,194.77 | 5% |
and
Ave Yrs to IPO (Slowest) | Avg Valuation at IPO | Time-Value Correlation |
12.5 | $385,006,675.55 | -58% |
There is no real correlation for the fastest to IPO group. The slowest to IPO group is highly negatively correlated to time to IPO. So the longer they take the lower the IPO value becomes. Based on this fastest to the market group, and if things continue, there would be 2 companies every month being founded that will eventually IPO in about 4 years. Let’s explore how these companies got to the IPO:
The full list is below:
Company | Categories | Years to IPO | Valuation |
BioXcel Therapeutics | Biotechnology | 1.2 | $167,000,000.00 |
Allogene Therapeutics | Biotechnology, Health Diagnostics, Pharmaceutical | 1.8 | $2,074,000,000.00 |
Equillium | Biopharma, Biotechnology, Life Science | 1.8 | $234,000,000.00 |
resTORbio | Biopharma, Clinical Trials, Medical | 2.1 | $410,000,000.00 |
Evelo Biosciences | Biotechnology, Medical, Therapeutics | 3.4 | $509,000,000.00 |
MeiraGTx | Biotechnology, Health Care, Therapeutics | 3.4 | $407,000,000.00 |
Aptinyx | Biopharma, Biotechnology, Medical | 3.5 | $520,000,000.00 |
Magenta Therapeutics | Biotechnology, Medical, Therapeutics | 3.5 | $515,000,000.00 |
Avrobio | Biotechnology, Genetics, Health Care | 3.5 | $440,000,000.00 |
Forty Seven | Biotechnology, Clinical Trials, Health Care | 3.5 | $479,000,000.00 |
Gritstone Oncology | Biotechnology, Health Care, Natural Resources, Therapeutics | 3.7 | $432,428,295.00 |
Orchard Therapeutics | Biotechnology, Genetics, Health Care, Health Diagnostics | 3.8 | $1,176,000,000.00 |
Eyenovia | Biotechnology, Manufacturing, Pharmaceutical | 4.1 | $99,000,000.00 |
Solid Biosciences | Biotechnology, Genetics, Manufacturing, Medical | 4.1 | $546,000,000.00 |
UNUM Therapeutics | Biotechnology, Health Care, Therapeutics | 4.2 | $355,000,000.00 |
Autolus Limited | Biopharma, Medical, Pharmaceutical | 4.5 | $657,000,000.00 |
LogicBio Therapeutics | Biotechnology, Genetics | 4.8 | $219,377,990.00 |
Eidos Therapeutics | Biopharma, Biotechnology, Pharmaceutical | 4.9 | $608,000,000.00 |
Tricida | Biotechnology, Health Care, Pharmaceutical | 5.5 | $763,000,000.00 |
Rubius Therapeutics | Biotechnology, Health Care, Therapeutics | 5.5 | $1,778,000,000.00 |
Arvinas | Biotechnology, Health Care, Pharmaceutical, Therapeutics | 5.7 | $514,500,000.00 |
Twist Bioscience | Biotechnology, Chemical, Health Care | 5.8 | $372,400,000.00 |
Evolus | Biotechnology | 6.1 | $283,000,000.00 |
Allakos | Biotechnology, Health Care, Therapeutics | 6.6 | $728,000,000.00 |
Guardant Health | Biotechnology, Health Care, Health Diagnostics | 6.8 | $1,587,000,000.00 |
Translate Bio | Biotechnology, Genetics, Medical, Therapeutics | 7.5 | $582,000,000.00 |
ASLAN Pharmaceuticals | Biotechnology, Medical, Pharmaceutical | 8.3 | $1,120,000,000.00 |
Genprex, Inc. | Biopharma, Biotechnology, Pharmaceutical | 9.2 | $65,000,000.00 |
UNITY Biotechnology | Biotechnology, Health Care, Medical | 9.3 | $712,000,000.00 |
Kodiak Sciences | Biotechnology, Health Care, Therapeutics | 9.8 | $365,000,000.00 |
Crinetics Pharmaceuticals | Biotechnology, Pharmaceutical, Therapeutics | 10.5 | $391,000,000.00 |
Principia Biopharma | Biopharma, Biotechnology, Life Science | 10.7 | $386,000,000.00 |
Inspire Medical Systems | Biotechnology, Health Care, Medical Device, Therapeutics | 11.3 | $323,000,000.00 |
Adial Pharmaceuticals | Biotechnology, Health Care, Pharmaceutical | 11.6 | $32,690,000.00 |
Xeris Pharmaceuticals | Biotechnology, Health Care, Pharmaceutical | 13.5 | $296,000,000.00 |
Liquidia Technologies | Biopharma, Nanotechnology, Therapeutics | 14.6 | $166,000,000.00 |
Neuronetics | Biotechnology, Medical Device, Therapeutics | 15.5 | $284,000,000.00 |
Aridis Pharmaceuticals | Biotechnology, Content Discovery, Health Care, Pharmaceutical | 15.6 | $102,573,796.00 |
BioNano Genomics | Biotechnology, Genetics, Health Diagnostics, Medical | 15.6 | $58,182,478.00 |
Sutro Biopharma | Biotechnology, Information Technology, Medical | 15.7 | $342,000,000.00 |
PhaseBio Pharmaceuticals | Biotechnology, Medical, Medical Device, Pharmaceutical | 16.8 | $119,000,000.00 |
Vaccinex | Biotechnology, Clinical Trials, Health Care | 17.6 | $137,700,588.00 |
Gamida Cell | Biotechnology, Medical Device, Therapeutics | 20.8 | $165,000,000.00 |
Sol-Gel Technologies | Biotechnology | 21.1 | $225,000,000.00 |
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